Threats to Environment and Public Health in Cox's Bazar posed by Rohingya Influx have become a major concern. Aid groups and environmentalists have warned against possible outbreak of diseases and environmental disasters as Bangladesh built the world's largest refugee camp for Rohingya who fled to the country following deadly violence in Myanmar's Rakhine State. The clearing of forest and hills in Cox's Bazar, the country's most popular tourist destination, would be disastrous for the environment. Environment and biodiversity of Cox's Bazar have already taken blows with the chopping down of thousands of trees and leveling of hills. Cutting of hills for settlements triggers landslides during the monsoon period. Nevertheless, there is impact on eco-system that refers to natural forests, protected areas and critical habitats, vegetation, wildlife, and marine and freshwater etc. It is a matter of regret that no solution was found till 2018 and the number of refugee plights hase been gradually increasing to the extent. Experts opine that Rohingya plights are vehemently affecting on the environment and public health. This study has examined the environmental and public health related threats of Rohingya influx from Myanmar on the local individuals of Cox's Bazar region. The possible guidelines to sort it out have also been analyzed here. The researchers have applied systematic review method to conduct this study.